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doi: 10.1038/s41392-024-01743-1 54 MakrisA

Agouti-related peptide neural circuits mediate adaptive behaviors in the starved state
One of those dual agonists, tirzepatide (Mounjaro/Zepbound, Eli Lilly), was associated with a mean 14.7% weight loss for adults with overweight or obesity and type 2 diabetes in the SURMOUNT-2 trial compared with a 3.2% weight loss with placebo

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B vitamins are also water-soluble, which means any excess leaves your body through urine

[DOI] [PubMed] [Google Scholar] 37.Vitamin B2 Deficiency
