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Introduction Brain disease, including brain cancers and central nervous system (CNS) disorders, are among the most prevalent, devastating and inadequately treated conditions

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The half-life differential has profound implications for steady-state hormone concentrations achievable in research
Selenomethionine (25-500 M, 24 h) inhibits TBHP-induced oxidative stress and mitochondrial division by activating the Nrf2 pathway, thereby inhibiting the apoptosis of nucleus pulposus cells (NPCs) and improving intervertebral disc degeneration (IDD) [3]

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Furthermore, the expression of IGF-1 is silenced in senescent fibroblasts in vitro
