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PP2A activation leads to subsequent inactivation of survival proteins such as Akt, thus contributing to apoptosis 62

To this end, multiple studies reported matrix metalloprotease- and ADAM-dependent cleavage sites at Arg31-Leu32 and Pro52-Leu53 that were inhibited by O-glycosylation at Ser 37 /Ser 41 (Goth et al., 2017
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Del Rio et al., 2012

doi:10.23812/20-339-a Tanaka H

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