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GSTs are reported to catalyze the conjugation of GSH with electrophilic sites of diverse substances, including insecticides and plant-derived toxins like xanthotoxin, sesquiterpene lactones and ITCs 24,33,55,56,57
Conversely, super-fast or rapid metabolizers (individuals with highly active CYP isoforms) can have altered drug responses by due to substantially lowered active drug lifespan

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doi: 10.1007/s004410050976 70 DerouicheARauenT

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