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A phase 1 clinical trial in RTT patients found no adverse effects of recombinant human IGF-1 (rhIGF-1) (Khwaja et al

[DOI] [PubMed] [Google Scholar] 43.Traina G, Bernardi R, Rizzo M, Calvani M, Durante M, Brunelli M

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Already in the 1940s, Charles Huggins and his colleagues demonstrated the effectiveness of ADT through surgical castration, which removes the major source of systemic androgen synthesis, as a treatment for advanced metastatic CaP [5, 6]

Carnitine infusions increased glucose metabolism in healthy adults when assessed using a hyperinsulinaemic euglycaemic clamp, owing to a non-oxidative process that leads in glycogen accumulation (Stephens et al., 2006, Stephens et al., 2007)

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