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A complex interplay thus exists between PD-L1 expression and 2M loss in LS [76]

As such, fingolimod is unselective as to which receptors it binds, probably spoiling its effects on the CNS when compared to newer drugs

However, biofilm-mediated disruption of granulation tissue migration interferes with re-epithelialization, angiogenesis, and skin restoration [49]

FOXO4-DRI induces keloid senescent fibroblast apoptosis by promoting nuclear exclusion of upregulated p53-serine 15 phosphorylation

This damage includes DNA strand breaks, which disrupt the expression of essential genes such as proto-oncogenes, oncogenes, and genes involved in DNA repair, thus facilitating tumorigenesis [89,90]

doi: 10.1073/pnas.96.12.7088
