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[DOI] [PMC free article] [PubMed] [Google Scholar] 81.Gorovits B., Azadeh M., Buchlis G., Fiscella M., Harrison T., Havert M., Janetzki S., Jawa V., Long B., Mahnke Y.D., et al

B12 is needed for all brain and nervous system activity, energy production, formation of blood, cell metabolism, DNA synthesis, fatty acid synthesis, and homocysteine metabolism

Acknowledgements This work was supported by grants NIH R35HL135828 (Y.-J.H.), NIH R01HL137268, R01HL085646, R01HL138708, R21AG055325 (Av.dV.), NIH R01HL122383 and R01HL141364, RO1HL136917 (V.A.)

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Moreover, NAC proved to be the most effective option compared to metformin and placebo as it was the only one that significantly decreased fasting blood glucose

MLCK-mediated phosphorylation of myosin light chain impairs TJ structure and elevates intestinal permeability [66]