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doi: 10.3389/fphar.2026.1783888 Received 08 January 2026 Revised 23 February 2026 Accepted 23 March 2026 Published 15 April 2026 Volume 17 - 2026 Edited by Jos Roberto de Oliveira Ferreira, Universidade Estadual de Cincias da Sade de Alagoas, Brazil Reviewed by Ruolan Li, University of Electronic Science and Technology of China, China Ramoji Kosuru, Versiti Blood Research Institute, United States Updates Copyright 2026 Scenna, Bej, Cesare, Persichitti, Cimini, DAngelo and Castelli

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72 Redox regulation, control of reduction/oxidation of the disulfide bonds, as well as phosphorylation are the two major post-translational modifications of proteins

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Detox Pathways Explained

These challenges span mechanistic understanding, therapeutic design, and clinical validation