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The symmetry of the funnel plot was further evaluated by Egger's linear regression test [6]

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doi: 10.1126/scitranslmed.3006585

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Data normality was assessed using the Shapiro-Wilk test, and homogeneity of variance was tested using Levenes test

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It is worth emphasizing that the hypoxia microenvironment induced by the E-P-OS network itself can directly activate the transcription of glycolysis-related genes such as glucose transporter 1 and lactate dehydrogenase A via HIF-1, thereby further enhancing glycolysis and ensuring energy supply for fibroid cells under hypoxic conditions [108]

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Both forms require identical storage conditions (20C or 28C for lyophilized, 28C for reconstituted), but CJC-1295 with DAC shows marginally faster degradation rates at room temperature in reconstituted form

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