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doi: 10.1016/j.jnutbio.2018.01.009

Our results uncover a new noncanonical function of PKM2 as a transcriptional coactivator of Nrf2, which cooperates with its metabolic function to divert glucose flux into the pentose phosphate pathway 55 and thereby generates sufficient GSH for ROS detoxification

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NAD+ IM shot delivers nicotinamide adenine dinucleotide directly into the muscle to support cellular energy production, improve metabolism, and potentially enhance mental clarity and recovery

TGF1-induced suppression of glutathione antioxidant defenses in hepatocytes: caspase-dependent posttranslational and caspase-independent transcriptional regulatory mechanisms