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Although the structure and transcriptional regulation of mtDNA differ from nDNA, emerging evidence suggests that mtDNAnDNA interactions are essential for cellular homeostasis and developmental competence in mammalian biology [6, 7]

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In Alzheimer disease specifically, BDNF deficits are most pronounced in the hippocampus, entorhinal cortex, and prefrontal cortex, the regions earliest and hardest hit by the disease

He stressed that SIP funds must be spent based on the five year development plans and projected budgets estimate as approved by the Joint Provincial Planning and Budget Priority Committee (JPP & BPC) and District Development Authority (DDA)

Clinical trials are ongoing to investigate the use of Dihexa in Parkinsons disease, and early findings are encouraging