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Successful and Unsuccessful Brain Aging in Pets: Pathophysiological Mechanisms behind Clinical Signs and Potential Benefits from Palmitoylethanolamide Nutritional Intervention

In many cases, beneficial effects can be chalked up to antioxidant activity, while the coenzymes role in the electron transport chain can account for some others

Bailey, MR First in Human Clinical Trial of Ultrasonic Propulsion of Kidney Stones J Urol 195 4P1: 956-64

It is important to emphasise that these potential benefits are largely theoretical or extrapolated from separate studies, rather than proven through robust clinical trials of the combination