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In addition to the 28-kDa cleavage product of the BDNF precursor, the 14-kDa mature BDNF is generated after cleavage of proBDNF by furin-like protein convertases PACE4, PC1, or PC5 (Mowla et al

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Joel B Mason, TuftsUSDA Human Nutrition Research Center on Aging, Boston, MA, USA

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