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Increases in the plasma membrane content of transporters stem from an increase in the rate of recruitment of new transporters into the plasma membrane, deriving from a special pool of preformed transporters localized in the cytoplasm

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This improvement, however short-lived, shows that metals and other toxins are at the root of many of the symptoms, and a multi-modality detoxification would likely produce a longer lasting recovery

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doi: 10.3389/fphar.2026.1767206 Received 14 December 2025 Revised 01 June 2026 Accepted 08 June 2026 Published 30 June 2026 Volume 17 - 2026 Edited by Nidhi Jalan-Sakrikar, Mayo Clinic, United States Reviewed by Slaan Pavlovi, University of Belgrade, Serbia Uro akar, University of Belgrade, Serbia Seddik Hammad, Heidelberg University, Germany Updates Copyright 2026 Philips, Sreemohan, Baby, Theruvath, Oommen, Ahamed, Tharakan and Augustine