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Features and data imputation Classifying a regions stage in a particular year was based on 16 possible features: (1) CD incidence

Its core functions are calculating topological properties such as node degree and clustering coefficient through the NetworkAnalyzer plugin, identifying closely connected gene modules using the Molecular Complex Detection (MCODE) plugin, and screening key hub genes with the CytoHubba plugin (Ma et al., 2021

Aging significantly elevates ROS and inflammation that together exacerbate cardiometabolic and vascular diseases

Bacterial cells have an enormous capability to acquire various antibiotic resistance mechanisms

Why B12 Matters B12 deficiency becomes more common with age due to decreased absorption Many adults do not get enough B12 from diet alone Certain conditions (e.g., anemia, fatigue) may require supplementation Oral supplements are not always reliably absorbed Contact Details 2764 Aborn Road, San Jose, CA, USA

1997 Nov-Dec Cristiana Paul, David M Brady