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In the general population, adequate dietary selenium intake is safe and beneficial for human health, with a recommended daily intake of 55 g for adults, 0.2 g/kg for children, and 6575 g for pregnant and lactating women [91]

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doi: 10.1126/science.1227157

Recently, protein S -mycothiolation, a reversible post-translational thiol-modification, was discovered as an important thiol protection mechanism that protects active-site cysteine residues of key enzymes against irreversible overoxidation to sulfonic acids 18

A primary reason is poor blood supply