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These damages can impair the cells repair mechanisms and the stability of genetic information, ultimately influencing cell survival

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This mechanism of eNOS uncoupling is unique in that it occurs in the reductase domain, unlike other uncoupling mechanisms that occur in the oxygenase domain, and can be inhibited by L-NAME (Chen et al., 2010)

In addition, the hydrolysed products of other nucleotides of triphosphates have synergistic effects with adenosine

22 Ostman, B., Sjdin, A., Michalsson, K

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