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(34798964) drug interactions Phenytoin is cleared by CYP2C9 (~90%) and 2C19 (~10%), leading to drug-drug interactions

however, if tissue malfunction persists, para-inflammation can turn from a beneficial and protective response to a detrimental and damaging process, inducing a continuous inflammatory state, leading to the chronicity of the disease [10, 16]

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Rec., recurrent or metastatic cancer

A comprehensive literature search yielded 153 studies, 13, published from 1989-2007, were deemed eligible