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H.DehghanG.MehdipourM.Teimuri-MofradR.PayamiE.SheibaniN.et al (2019)

Likewise, SAMP8 mice, which are used as a model for Alzheimers disease, show increased formaldehyde-producing semicarbazide-sensitive amine oxidase (SSAO) and decreased ADH5 activity in the brain [31]

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However, disruption of other mitochondrial enzymes/complexes of cerebral energy metabolism (e.g., -ketoglutarate dehydrogenase complex (KGDHC) and pyruvate dehydrogenase complex (PDHC)) may also contribute to decreased energy production in neurodegenerative disease (reviewed by Gibson et al., 2005, Kiss et al., 2013)

doi: 10.3390/nu14112275 496 de Jess Romero-PradoMMCuriel-BeltrnJAMiramontes-EspinoMVCardona-MuozEGRios-ArellanoABalam-SalazarLB

I., Raptis, S