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Monomethyl fumarate was approved by the FDA in April 2020
The American Journal of Psychiatry, 152 (5), 792794

Las limitaciones actuales de la investigacin incluyen la ausencia de ensayos clnicos aleatorizados de gran envergadura en humanos, una comprensin an parcial de los mecanismos moleculares precisos y una falta de datos farmacocinticos detallados en humanos

Dementia Loss of appetite Confusion A racing or fast heartbeat Balancing problem Tingling or numbness in hands or feet Pernicious anemia (reduction in RBCs) Pernicious anemia is not common in people younger than 30 years of age

doi: 10.1159/000047299

The formation of LA inhibitory fragments presents a pharmacological dilemma, because it has the potential to limit efficacy of the parent LA molecule
