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Heterogeneity of multiple sclerosis lesions: implications for the pathogenesis of demyelination
2015 May;40(6):1405-16
Published rodent oral protocols have used 10-50 mcg/kg/day
[DOI] [PMC free article] [PubMed] [Google Scholar] 111.Drouin C, Darracq, L, Trovero, F, Blanc, G, Glowinski, J, Cotecchia, S and Tassin, JP
IGF-DES activates these same pathways via IGF-1R but without the prior IGFBP buffering that attenuates native IGF-1 signalling
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