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When histamine binds to the H3 receptor, the molecular gate closes and prevents histamine from being released (bottom left)

IV and short-duration oral trials METAOD001-004 enrolled smaller groups of healthy or obese men with single doses or 1-week dosing across IV (25-400 mcg/kg) and oral (9-54 mg) routes

Licensed medical providers must oversee treatment, and informed consent is required

Use of unapproved Pfizer-BioNTech COVID-19 Vaccine for active immunization to prevent COVID-19 under this EUA is limited to the following (all requirements must be met): 1

We dont have long-term human safety data

Not for injection