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Description
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The increase of tHcy showed no causal link with the improvement of MAFLD-related inflammatory, metabolic and histological pattern
While inhibition of xCT suppresses cystine uptake and induces ferroptosis, we identified -glutamylcyclotransferase (GGCT), a key enzyme in glutathione (GSH) degradation, as a metabolic compensation pathway that regenerates cysteine to sustain redox homeostasis
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