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in the ninth trial, the dose was 15 mg/kg/day for 182 days

Plays a role in energy metabolism during exercise

Although our findings argue against further exploration of ALCAR/ALA (at least at the doses used here) for treatment of bipolar depression, other mitochondrial-enhancing compounds, such as N-acetylcysteine (NAC), coenzyme Q10 (CoQ10), and creatine monohydrate, might have more potent effects on mitochondrial functioning and hence greater antidepressant efficacy
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Muscle Nerve (2005) 32:6338
