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Our studies highlight the selective regulation of an acyl-lipoyl conjugate (thioester bond), which is distinct from the role of Sirtuins (SIRTs) in cleaving acyl modifications from lysine residues (amide bonds)

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Differential effects of chlorogenic acid on various immunological parameters relevant to rheumatoid arthritis

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Conversion of the mitochondrial HMG-CoA, derived from leucine catabolism, to acetoacetyl-CoA and acetoacetate is catalyzed by HMG-CoA lyase (encoded by the HMGCL gene)