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10.1073/pnas.1120210109 3 CorejovaA.JanosikovaD.PospisilovaV.RauovaD.KyselovicJ.HrabovskaA

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Additionally, SIRT1 has been reported to deacetylate and inhibit p53, a tumor suppressor that promotes ferroptosis under certain conditions [11]

Furthermore, in the field of intervertebral disc tissue engineering, cell-free therapeutic strategies based on hydrogels primarily include drug delivery, controlled release of cytokines, and gene therapy
