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doi: 10.1038/ng1743

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Most community protocols start cagrilintide at 0.25 mg/week once tirzepatide is established, then step up every 4 weeks to 0.5, 1.0, 1.7, and 2.4 mg/week

Percentage of participants reaching weight loss thresholds Raw averages obscure individual variation

A specific variant of the MOTS-C gene also shows up in Japanese centenarians at higher rates than in the general population
