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Factors such as age, liver function, body composition, and overall metabolic rate all influence how quickly EtG is produced and eliminated

A report from the Framingham Offspring Study of 2,999 adults found the following average daily B12 intakes, including fortified foods and supplements (Tucker, 2000): Age 26-49: 8.9 g Age 50-64: 8.7 g Age 65-83: 8.5 g A 2015-2016 National Health and Nutrition Examination Survey of over 4,500 adults 60 years and older found the following average daily B12 intakes (USDA NHANES, 2019): Male non-supplement users (68% of men): 4.5 g Male supplement users: 5.3 g from food plus 326 g from supplements Female non-supplement users (63% of women): 3.6 g Female supplement users: 3.8 g from food plus 520 g from supplements European Food Safety Authoritys Recommendations In 2015, the EFSA released recommendations for B12 intake across Europe

For anyone undertaking a liver cleanse or seeking long-term liver support, milk thistle is the most evidence-based choice available over the counter

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[DOI] [PMC free article] [PubMed] [Google Scholar] 156.Morris G, Stubbs B, Khler CA, Walder K, Slyepchenko A, Berk M, et al

Notably, stem cell therapies are presently in preclinical stages, prompting ethical concerns and diverse opinions