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Targeted effects : L-carnitine offers targeted efficacy for hard-to-treat areas resistant to diet or exercise

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In fact, Metformin may have a significant impact on longevity, positively impact several hallmarks of aging, and even extend healthspan

However, some limitations should be noted

Enhancing GSH, mainly through NAC, GSH precursors or pro-GSH compound administration, becomes a potential treatment option for SARS-CoV-2 infection and COVID-19 disease by reducing oxidative stress and cytokine expression especially in diabetic patients at risk of more severe disease (Singh et al., 2022)