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To the best of our knowledge, human pharmacokinetic studies investigating these aspects in detail in a procyanidin-rich pine bark extract, have been only performed for Pycnogenol

This deterioration of brain function is due to the livers incapacity to remove blood toxins, such as ammonia and lipopolysaccharides, which causes systemic inflammation and activation of the circulatory neutrophils [146]

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Equal amounts of protein (30 g per lane) were separated by SDS-PAGE and transferred to PVDF membranes (Millipore, USA)

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