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Nrf2 once activated, binds to the antioxidant response element (ARE) located at the regulatory regions of the genes of the antioxidant enzymes and induces transcription of the antioxidants genes (Morinho et al., 2014)

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Considerations in translating of NCMPs to the clinic The lung itself is an extremely complex structure, functioning as a significant barrier protect the respiratory system from pollutant particles and microorganisms

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