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In UC and other inflammatory diseases, the Th/Treg balance is disrupted, usually resulting in increased activity or increased numbers of Th17 cells and decreased function or a decreased number of Treg cells

Clinical trials have demonstrated substantial improvements in hemoglobin A1c reduction (up to 2.5% decrease) in diabetes patients, while weight loss of up to 20% was observed primarily in adults with obesity without diabetes in the SURMOUNT-1 trial

29 A high-fructose diet can also trigger symptoms of metabolic syndrome and increase oxidative stress and inflammation, reducing glutathione

On the other side, long-term human safety data, standardized dosing protocols, and controlled efficacy trials remain extremely limited

First, cows supposedly need to be supplemented with Vitamin B12