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In this experiment, the high protein diet can promote intestinal secretion of GLP-1, improve FGF21 resistance, upregulate LKB1 to activate the AMPK pathway, downregulate the expression of SERBP-1c mRNA and protein in the liver, and ultimately inhibit liver lipid synthesis [50]

Immunopathology and Disease Development The literature indicates that innate immune responses triggered by complement system activation and high titers of nAbs can lead to severe complications

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Oxidation of lipid rafts and synaptic vesicle membranes alters voltage-gated channels, N-methyl-D-aspartate (NMDA), -amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPA) and kainate receptor (KAR) localization consequently impairing neuronal function and making neurons vulnerable to excitotoxicity leading to neurodegeneration (Mattson, 1998

Impact of probe compound in MRP2 vesicular transport assays