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Description
chronic symptoms wane and wax over time
FEBS Open Bio 12 , 739757 (2022)
In contrast to class I GRXs, class II GRXs have no reductase activity in enzyme assays with low molecular weight substrates bis(2-hydroxyethyl)disulfide (HED) or L-cysteine-glutathione-disulfide (Cys-SG) 13
For instance, Rathore et al
Research status FDA-approved for HIV lipodystrophy
This is a mechanistic inference, not a human finding, but it illustrates why unregulated IGF-1R agonism is not treated casually in the scientific literature
