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They are not approved for human consumption
Protein interaction studies have led to the proposed architecture of these PG synthesis complexes, but it is poorly understood how dynamic some of the observed (and possibly yet-to-be identified) interactions are
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Overall, S1P regulates polarization in macrophages, promotes immune responses in T cells, maintains immune homeostasis in B cells, and regulates migration and activation in neutrophils and mast cells
Biochim Biophys Acta Mol basis Dis 1863:24962507 Hutchings CJ, Koglin M, Marshall FH (2010) Therapeutic antibodies directed at G protein-coupled receptors
