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The HMP shunt has two phases: the oxidative phase and the non-oxidative phase

Inhibition of tyrosinase and melanin synthesis Glutathione interferes with the activity of tyrosinase, the ratelimiting enzyme that converts tyrosine into dopa and dopaquinone, the first steps in melanin production

doi: 10.3389/fimmu.2012.00360 149 FadiniGPMenegazzoLScattoliniVGintoliMAlbieroMAvogaroA

Low Levels of Serum Total Vitamin B12 Are Associated with Worse Metabolic Phenotype in a Large Population of Children, Adolescents and Young Adults, from Underweight to Severe Obesity

Proc Natl Acad Sci U S A 105(48):1896418969

The meta study found that Lactobacillus gasseri decreased body weight, BMI, waist circumference, body fat mass or fat percentage in those with overweight or obesity