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Disruption of oxidative phosphorylation by deleting cytochrome c oxidase assembly factor 10 leads to lysosomal and mitochondrial defects, resulting in LPO and ferroptosis of cardiac cells (Ahola et al., 2022)

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Histopathological analyses demonstrated that the SL-7 wafer outperforms Plendil in safeguarding cardiac tissue

In the nucleus, p65 coordinates gene transcription by recruiting coactivators (e.g., CREB-binding proteins (CBP)) or corepressors (e.g., histone deacetylases (HDACs)) (Liu et al., 2008) (Figure 2B)

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How does disrupted central glucose sensing cause systemic metabolic disorders