metabolic acidosis and glutathione View of Acetaminophen, the missing anion gap in the patient with Unexplained metabolic acidosis in critically

These data predict that the greatest clinical impact will be in individuals with compromised brain HGF/c-Met systems as present in early-stage AD

Aggarwal A, Aggarwal N, Nagral A, Jankharia G, Bhatt M

The process is similar to getting a blood transfusion

PMID 18366757

J.AlicN.ThorpeG

Toxic solvent residues DMF (dimethylformamide) Known liver toxin Associated with reproductive toxicity Must be removed to extremely low limits in GMP drugs DCM (dichloromethane / methylene chloride) Probable human carcinogen Central nervous system depressant Dangerous even in small amounts if injected TFA (trifluoroacetic acid) Corrosive Can remain in peptides as unmeasured TFA salt Pharmaceutical products often convert TFA salts to safer counterions Without validated HPLC, mass spectrometry, and residual solvent testing, patients may be injected with harmful chemical contaminants