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Hobbs CA, Sherman SL, Yi P, Hopkins SE, Torfs CP, Hine RJ, et al

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In UC mice, glutamine (Gln) reduced oxidative stress-induced injury by inhibiting the PI3K/Akt signaling pathway (169)
However, it wasnt until 2012, that Brent R Stockwell et al

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Caloric restriction in humans: impact on physiological, psychological, and behavioral outcomes