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Multiple hypothesis correction was performed using the BenjaminiHochberg method or the 2-stage linear step-up procedure of Benjamini, Krieger, and Yekutieli, where indicated
We also hypothesize that -alanine may help regulate metal dyshomeostasis, which leads to ROS production
Overall, this suggests there was no worsening of kidney function
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The benefit was greatest when supplemented at daily doses of 2,000 mg per day and was strongest in higher quality RCTs
