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Discussion Cell proliferation is regulated by a variety of mechanisms working to allow the activation and repression of growth stimulatory genes

This immunosuppressive environment is maintained by several cytokines such as IL-6 and TNF-, which activate NF-B/STAT3 signaling, and chemokines such as CCL2 and CXCL12, which bring in monocytes (107, 108)

The energy of the proton gradient flowing in the forward direction from the intermembrane space through the F o domain of the complex is coupled to the synthesis of ATP

These compounds act by dissipating the proton gradient across the mitochondrial inner membrane

Int J Mol Sci 17(12):2124