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In addition, there is a U-shaped association between selenium exposure and some diseases, such as type 2 diabetes and fractures [117]

[DOI] [PMC free article] [PubMed] [Google Scholar] 79

Ali ZaidiSSFatimaFAli ZaidiSAZhouDDengWLiuS

Activation of NF-k antagonizes programmed cell death induced by TNFR1, and GSH depletion has been shown to down-regulate TNF-induced NF-k activation and sensitize to apoptotic cell death [123]

In contrast, inducing autophagy with rapamycin (100 nM) attenuated SIPS

Ayoub KF, Pothineni NVK, Rutland J, Ding Z, Mehta JL
