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W: Weeks, g: grams, d: days, l: milliliter, min: minutes, L-carnitine L-carn, SD: standard deviation, N: number of subjects, 1: subjects that did not use carn., 2: subjects used carn, SMD: standard mean differences, SE: standard error, CI: confidential intervals

This data suggest that the use of T4 therapy (even if given at supra-physiological levels) cannot reasonably achieve normal tissue levels of T3

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Therefore, a more homogenous sample of bipolar patients could be more biologically predisposed to benefit from ALCAR/ALA treatment

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[47] [263] In turn, N -methylphenethylamine is metabolized from phenethylamine by phenylethanolamine N -methyltransferase, the same enzyme that metabolizes norepinephrine into epinephrine