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Vitamin B12 plays a crucial role in maintaining cognitive function, and its deficiency is strongly associated with cognitive decline and memory impairment
The first peptide drug insulin was isolated in 1921 and became commercially available in 1923
B12 injections are generally very safe with minimal side effects
This effect might be particularly important in the clinical management of PDN, given the close association between neuropathic pain and sleep disturbances [26]
