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If you notice persistent joint discomfort, recurring flare-ups, or difficulty managing pain despite treatment, its important to schedule an evaluation

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Additionally, data indicate that women with previous neural tube defect (NTD) affected pregnancies should increase their folic acid intake to 4 mg/day PO during the period of greatest risk (1 month before and the 3 months after conception)

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Individuals with sensitive skin may benefit from patch testing before regular use