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however, the findings have not yet been released (NCT01684683)

This plasmid pool was used to generate a lentiviral library, which was transfected into HEK-293T cells and used to generate viral supernatant as described above

In autoimmune conditions, activated T cells accumulate ROS-induced oxidative DNA damage, creating a vicious cycle that further exacerbates inflammatory responses

doi: 10.1007/BF01076518

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Further, substitution of Arg for Sec may not be a random amino acid insertion, as two of the six Arg codons (CGA and AGA) have only a single base difference with the UGA codon