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Dhillon N, Kopetz S , Del Fabbro E, Reddy S, Bruera E

The outer mitochondrial membrane harbors mitochondrial antiviral signaling protein (MAVS) which signals the presence of cytosolic viral double-stranded RNA, leading to the activation of nuclear factor kappa B (NF-B) and interferon regulator factor 3 (IRF3) to induce the expression of pro-inflammatory cytokines and type I interferon (IFN

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Transformation of Psoralen and isopsoralen by human intestinal microbial in vitro, , and the biological activities of its metabolites

Taken together, glutamine dependency may be a particular metabolic vulnerability of cancer cells, and glutaminolysis-targeting strategies could be promising approaches for glutamine-addicted cancer therapy

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