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Their yield, structural integrity, and biological activity are highly dependent on the extraction process (55)

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Effects of olive leaf polyphenols on male mouse brain NGF, BDNF and their receptors TrkA, TrkB and p75

Similarly, in Nrf2-KO mice, there are higher levels of proinflammatory genes such as IL-1, IL-6, IL-8, iNOS , and COX-2 , and a decrease in the expression of antioxidant enzymes like hemeoxygenase-1 and GST Mu-1 (93)

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They found that the combination of these growth factors displayed a more significant maximum load and tensile stress and inhibited scar formation compared to the IGF-1 alone group, suggesting that combination of IGF-1 and TGF- is more effective than IGF-1 alone in the treatment of tendon injury (Xiang et al., 2018)