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Blockade of GCH1/BH4 Axis Activates Ferritinophagy to Mitigate the Resistance of Colorectal Cancer to Erastin-Induced Ferroptosis

This approach enables truly site-specific, stoichiometric PEGylation that yields a homogeneous product with simplified analytical characterization and regulatory documentation

We also analyzed the expression of two marker genes, a cytosolic h-type thioredoxin (TRX, TH8) and a glucosyltransferase (UGT74E2), that were found to be strongly up-regulated in seedlings with low GSH content

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