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Jun 6 2021;18(1):57

The cell migration gene family DLX (such as DLX1, DLX2, DLX5/6) are homeodomain transcription factors that primarily govern the generation and migration of GABAergic interneurons in the forebrain

Tertiary amine modification enables triterpene nanoparticles to target the mitochondria and treat glioblastoma via pyroptosis induction

Ming-Wen Hu, orcid.org/0009-0001-5495-7110

Peroxidation of membrane results in huge compromise of the structural and functional integrity of the cell characterized by altered membrane permeability,17 dysfunctionality of membrane receptors,18 decreased activity of membrane-bound enzymes19 and increased membrane rigidity which decreases membrane fluidity.20 The possibility of free radicals directly attacking membrane proteins, induce lipid-lipid, lipid-protein and protein-protein cross linking also exist.21 Peroxynitrate (ONOO), a powerful oxidant is formed when O2 reacts with nitric oxide radical (NO) in the presence of arginine and NADPH-Oxidase enzyme